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1

Didactic analysis as the core of preparation of instruction (Didaktische Analyse als Kern der Unterrichtsvorbereitung)

Klafki, Wolfgang

Journal:

Curriculum Studies

Year:

1995

Language:

english

File:

PDF, 1.22 MB

english, 1995

2

DIE STUFEN DES PÄDAGOGISCHEN DENKENS

Klafki, Wolfgang

Journal:

Bildung und Erziehung

Year:

1954

Language:

german

File:

PDF, 531 KB

german, 1954

3

Improved electrophoretic separation and immunoblotting of beta-amyloid (Aβ) peptides 1–40, 1–42, and 1–43

Dr. Jens Wiltfang, Alexandr Smirnov, Beate Schnierstein, Georg Kelemen, Uta Matthies, Hans-Wolfgang Klafki, Matthias Staufenbiel, Gerald Hüther, Eckhardt Rüther, Johannes Kornhuber

Journal:

ELECTROPHORESIS

Year:

1997

Language:

english

File:

PDF, 681 KB

english, 1997

4

Analysis of Amino-Terminal Variants of Amyloid-β Peptides by Capillary Isoelectric Focusing Immunoassay

Haußmann, Ute, Jahn, Olaf, Linning, Philipp, Janßen, Christin, Liepold, Thomas, Portelius, Erik, Zetterberg, Henrik, Bauer, Chris, Schuchhardt, Johannes, Knölker, Hans-Joachim, Klafki, Hans, Wiltfang,

Journal:

Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 1.84 MB

english, 2013

5

Development of a capillary isoelectric focusing immunoassay to measure DJ-1 isoforms in biological samples

Besong Agbo, D., Klafki, H., Poschmann, G., Seyfarth, K., Genius, J., Janßen, C., Stühler, K., Wurst, W., Meyer, H.E., Klingenspor, M., Wiltfang, J.

Journal:

Analytical Biochemistry

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

6

Capillary isoelectric focusing immunoassay as a new nanoscale approach for the detection of oligoclonal bands

Halbgebauer, Steffen, Haußmann, Ute, Klafki, Hans, Tumani, Hayrettin, Wiltfang, Jens, Otto, Markus

Journal:

ELECTROPHORESIS

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

7

Reduction of Disulfide Bonds in an Amyloidogenic Bence Jones Protein Leads to Formation of “Amyloid-Like” Fibrils in Vitro

KLAFKI, Hans-Wolfgang, PICK, Albert Israel, PARDOWITZ, Iancu, COLE, Thomas, AWNI, Lewa Adil, BARNIKOL, Heinz-Ulrich, MAYER, Frank, KRATZIN, Hartmut Dieter, HILSCHMANN, Norbert

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1993

Language:

english

File:

PDF, 1.33 MB

english, 1993

8

Schulnahe Curriculumentwicklung in Form von Handlungsforschung

Klafki, Wolfgang

Journal:

Bildung und Erziehung

Year:

1975

Language:

german

File:

PDF, 986 KB

german, 1975

9

Amyloid precursor protein truncated at any of the γ-secretase sites is not cleaved to β-amyloid

Paolo A. Paganetti, Maddalena Lis, Hans-Werner Klafki, Matthias Staufenbiel

Journal:

Journal of Neuroscience Research

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

10

Structural Design, Solid-Phase Synthesis and Activity of Membrane-Anchored β-Secretase Inhibitors on Aβ Generation from Wild-Type and Swedish-Mutant APP

Heinke Schieb, Dr. Sebastian Weidlich, Dr. Georg Schlechtingen, Philipp Linning, Dr. Gary Jennings, Dr. Margit Gruner, Prof. Dr. Jens Wiltfang, Dr. Hans-Wolfgang Klafki, Prof. Dr. Hans-Joachim Knölker

Journal:

Chemistry - A European Journal

Year:

2010

Language:

english

File:

PDF, 923 KB

english, 2010

11

A quantitative CE method to analyse tau protein isoforms using coated fused silica capillaries

Diego Bohoyo, Isabelle Le Potier, Céline Rivière, Hans Klafki, Jens Wiltfang, Myriam Taverna

Journal:

Journal of Separation Science

Year:

2010

Language:

english

File:

PDF, 261 KB

english, 2010

12

Electrophoretic Separation of βA4 Peptides (1–40) and (1–42)

Hans-W. Klafki, Jens Wiltfang, Matthias Staufenbiel

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 191 KB

english, 1996

13

Experimental verification of the effect of bridge formation in a direct methanol fuel cell

A.A. Kulikovsky, K. Klafki, K.Wippermann

Journal:

Electrochemistry Communications

Year:

2005

Language:

english

File:

PDF, 159 KB

english, 2005

14

Simultaneous analysis by capillary electrophoresis of five amyloid peptides as potential biomarkers of Alzheimer's disease

Romain Verpillot, Markus Otto, Hans Klafki, Myriam Taverna

Journal:

Journal of Chromatography A

Year:

2008

Language:

english

File:

PDF, 631 KB

english, 2008

15

Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation

J. Wiltfang, H. Esselmann, M. Bibl, A. Smirnov, M. Otto, S. Paul, B. Schmidt, H.-W. Klafki, M. Maler, T. Dyrks, M. Bienert, M. Beyermann, E. Rüther, J. Kornhuber

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 489 KB

english, 2002

16

Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: Evidence for novel Aβ species

Juan Manuel Maler, Hans-Wolfgang Klafki, Sabine Paul, Philipp Spitzer, Teja Wolfgang Groemer, Andreas Wolfram Henkel, Hermann Esselmann, Piotr Lewczuk, Johannes Kornhuber, Jens Wiltfang

Journal:

Year:

2007

Language:

english

File:

PDF, 249 KB

english, 2007

17

A method to prevent cross contamination during 2-DE by β-amyloid peptides

Heinke Schieb, Philipp Spitzer, Verena Riess, Jens Wiltfang, Hans W. Klafki

Journal:

Year:

2010

Language:

english

File:

PDF, 135 KB

english, 2010

18

CSF amyloid-β 1-38 and 1-42 in FTD and AD: Biomarker performance critically depends on the detergent accessible fraction

Mirko Bibl, Piotr Lewczuk, Hermann Esselmann, Brit Mollenhauer, Hans-Wolfgang Klafki, Volker Welge, Stefanie Wolf, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang

Journal:

PROTEOMICS - Clinical Applications

Year:

2008

Language:

english

File:

PDF, 312 KB

english, 2008

19

Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer’s disease

Volker Welge, Oliver Fiege, Piotr Lewczuk, Brit Mollenhauer, Hermann Esselmann, Hans-Wolfgang Klafki, Stefanie Wolf, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang, Mirko Bibl

Journal:

Journal of Neural Transmission

Year:

2009

Language:

english

File:

PDF, 258 KB

english, 2009

20

Carbon supported Ru–Se as methanol tolerant catalysts for DMFC cathodes. Part II: preparation and characterization of MEAs

K. Wippermann, B. Richter, K. Klafki, J. Mergel, G. Zehl, I. Dorbandt, P. Bogdanoff, S. Fiechter, S. Kaytakoglu

Journal:

Journal of Applied Electrochemistry

Year:

2007

Language:

english

File:

PDF, 1.90 MB

english, 2007

21

ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior

Bernd Lenz, Hans-Wolfgang Klafki, Thomas Hillemacher, Helge Frieling, Marion Clepce, Andrea Gossler, Norbert Thuerauf, Georg Winterer, Johannes Kornhuber, Stefan Bleich

Journal:

Addiction Biology

Year:

2012

Language:

english

File:

PDF, 436 KB

english, 2012

22

Immune complexes of auto-antibodies against Aβ1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients

Henkel, A W, Dittrich, P S, Groemer, T W, Lemke, E A, Klingauf, J, Klafki, H W, Lewczuk, P, Esselmann, H, Schwille, P, Kornhuber, J

Journal:

Molecular Psychiatry

Year:

2007

Language:

english

File:

PDF, 279 KB

english, 2007

23

Distinct fractional Aβ release patterns in human mononuclear phagocytes

Juan Manuel Maler, Philipp Spitzer, Hans-Wolfgang Klafki, Hermann Esselmann, Piotr Lewczuk, Johannes Kornhuber, Martin Herrmann, Jens Wiltfang

Journal:

Journal of Neuroimmunology

Year:

2009

Language:

english

File:

PDF, 286 KB

english, 2009

24

Evaluation of Live-Capture Techniques for Free-Ranging Wolverines

ERIC C. LOFROTH, RICHARD KLAFKI, JOHN A. KREBS, DAVE LEWIS

Journal:

Journal of Wildlife Management

Year:

2008

Language:

english

File:

PDF, 4.51 MB

english, 2008

25

Calpain inhibitor I decreases βA4 secretion from human embryonal kidney cells expressing β-amyloid precursor protein carrying the APP670/671 double mutation

Hans-W. Klafki, Paolo A. Paganetti, Bernd Sommer, Matthias Staufenbiel

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 605 KB

english, 1995

26

Adherence-dependent shifts in the patterns of β-amyloid peptides secreted by human mononuclear phagocytes

Juan Manuel Maler, Philipp Spitzer, Hans-Wolfgang Klafki, Hermann Esselmann, Mirko Bibl, Piotr Lewczuk, Johannes Kornhuber, Martin Herrmann, Jens Wiltfang

Journal:

Brain, Behavior, and Immunity

Year:

2008

Language:

english

File:

PDF, 441 KB

english, 2008

27

Optimisation of BACE1 inhibition of tripartite structures by modification of membrane anchors, spacers and pharmacophores – development of potential agents for the treatment of Alzheimer's disease

Linning, Philipp, Haussmann, Ute, Beyer, Isaak, Weidlich, Sebastian, Schieb, Heinke, Wiltfang, Jens, Klafki, Hans-Wolfgang, Knölker, Hans-Joachim

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 2.44 MB

english, 2012

28

P2-052: Chicken primary neuronal cells as a powerful model for studying tau phosphorylation, APP processing and Aβ generation

Juan Manuel Maler, Hans W. Klafki, Hermann Esselmann, Nikolaus Kunz, Sabine Paul, Johannes Kornhuber, Jens Wiltfang

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

29

P2-058: Pharmacological analysis of cellular models of PHF-type tau hyperphosphorylation

Hans Klafki, Gabi Huebinger, Sylvie LeCorre, Hanno M. Roder

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 54 KB

english, 2006

30

P2-157: Expression of CSF amyloid beta peptide patterns Alzheimer’s disease, dementia with Lewy bodies and Parkinson’s disease dementia

Mirko Bibl, Brit Mollenhauer, Hermann Esselmann, Piotr Lewczuk, Hans-Wolfgang Klafki, Katrin Sparbier, Alexandr Smirnov, Lukas Cepek, Claudia Trenkwalder, Eckart Ruther, Johannes Kornhuber, Markus Ott

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 69 KB

english, 2006

31

P1-071: High resolution 1d and 2d analysis of A-beta peptides in plasma, Csf and brains of APP23 transgenic mice

Hans W. Klafki, Heinke Schieb, Sabine Paul, Hermann Esselmann, Sabine Leuthäusser, Juan Manuel Maler, Mirko Bibl, Matthias Staufenbiel, Jens Wiltfang

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

32

Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes

Philipp Spitzer, Martin Herrmann, Hans-Wolfgang Klafki, Alexander Smirnov, Piotr Lewczuk, Johannes Kornhuber, Jens Wiltfang, Juan Manuel Maler

Journal:

Journal of Neuroinflammation

Year:

2010

Language:

english

File:

PDF, 1.73 MB

english, 2010

33

Current application of neurochemical biomarkers in the prediction and differential diagnosis of Alzheimer’s disease and other neurodegenerative dementias

Genius, J., Klafki, H., Benninghoff, J., Esselmann, H., Wiltfang, J.

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

2012

Language:

english

File:

PDF, 164 KB

english, 2012

34

THE LANCET. LONDON : SATURDAY, APRIL 14, 1855

Schieb, Heinke, Knölker, Hans-Joachim, Weidlich, Sebastian, Wiltfang, Jens, Klafki, Hans W.

Journal:

Year:

1855

Language:

english

File:

PDF, 732 KB

english, 1855

35

Profiling Of Membrane-anchored β-secretase Inhibitors In Cell Cultures

Schieb, Heinke, Knölker, Hans-Joachim, Weidlich, Sebastian, Wiltfang, Jens, Klafki, Hans W.

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

36

Modifications to urea SDS Aβ-PAGE facilitate the resolution of N-terminally truncated Aβ peptides and of Aβ forms longer than 42 residues

Haussmann, Ute, Esselmann, Hermann, Schieb, Heinke, Lehmann, Sabine, Klafki, Hans-Wolfgang, Wiltfang, Jens

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

37

Phagocytosis Is Associated With Increased Secretion Of N-terminally Truncated beta-amyloid Peptides In Human Mononuclear Phagocytes

Spitzer, Philipp, Klafki, Hans Wolfgang, Esselmann, Hermann, Wiltfang, Jens, Maler, Juan Manuel

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

38

Synthesis and release of the β-amyloid precursor protein by bovine chromaffin cells

Bieger, S., Klafki, H.-W., Unsicker, K.

Journal:

Neuroscience Letters

Year:

1993

Language:

english

File:

PDF, 276 KB

english, 1993

39

In situ measurement of the oxygen diffusion coefficient in the cathode catalyst layer of a direct methanol fuel cell

Wippermann, K., Klafki, K., Kulikovsky, A.A.

Journal:

Electrochimica Acta

Year:

2014

Language:

english

File:

PDF, 530 KB

english, 2014

40

High-Fat Diet Induced Isoform Changes of the Parkinson’s Disease Protein DJ-1

Poschmann, Gereon, Seyfarth, Katrin, Besong Agbo, Daniela, Klafki, Hans-Wolfgang, Rozman, Jan, Wurst, Wolfgang, Wiltfang, Jens, Meyer, Helmut E., Klingenspor, Martin, Stühler, Kai

Journal:

Journal of Proteome Research

Year:

2014

Language:

english

File:

PDF, 4.35 MB

english, 2014

41

Complete amino acid sequence determinations demonstrate identity of the urinary Bence Jones protein (BJP-DIA) and the amyloid fibril protein (AL-DIA) in a case of AL-amyloidosis

Klafki, Hans W., Kratzin, Hartmut D., Pick, Albert I., Eckart, Klaus, Karas, Michael, Hilschmann, Norbert

Journal:

Year:

1992

Language:

english

File:

PDF, 1.21 MB

english, 1992

42

Analysis of Amyloid-β Peptides in Cerebrospinal Fluid Samples by Capillary Electrophoresis Coupled with LIF Detection

Verpillot, Romain, Esselmann, Hermann, Mohamadi, Mohamad Reza, Klafki, Hans, Poirier, Florence, Lehnert, Stefan, Otto, Markus, Wiltfang, Jens, Jean-Louis, Viovy, Taverna, Myriam

Journal:

Analytical Chemistry

Year:

2011

Language:

english

File:

PDF, 1.51 MB

english, 2011

43

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides

Oberstein, Timo Jan, Spitzer, Philipp, Klafki, Hans-Wolfgang, Linning, Philipp, Neff, Florian, Knölker, Hans-Joachim, Lewczuk, Piotr, Wiltfang, Jens, Kornhuber, Johannes, Maler, Juan Manuel

Journal:

Neurobiology of Disease

Year:

2015

Language:

english

File:

PDF, 1.55 MB

english, 2015

44

Therapeutic approaches to Alzheimer's disease

Klafki, H.-W., Staufenbiel, M., Kornhuber, J., Wiltfang, J.

Journal:

Year:

2006

Language:

english

File:

PDF, 338 KB

english, 2006

45

An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice

Le Corre, S., Klafki, H. W., Plesnila, N., Hubinger, G., Obermeier, A., Sahagun, H., Monse, B., Seneci, P., Lewis, J., Eriksen, J., Zehr, C., Yue, M., McGowan, E., Dickson, D. W., Hutton, M., Roder, H

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 1.29 MB

english, 2006

46

The Carboxyl Termini of -Amyloid Peptides 1-40 and 1-42 Are Generated by Distinct -Secretase Activities

Klafki, H.- W., Abramowski, D., Swoboda, R., Paganetti, P. A., Staufenbiel, M.

Journal:

Journal of Biological Chemistry

Year:

1996

Language:

english

File:

PDF, 796 KB

english, 1996

47

-Amyloid Peptide Variants in Brains and Cerebrospinal Fluid from Amyloid Precursor Protein (APP) Transgenic Mice: COMPARISON WITH HUMAN ALZHEIMER AMYLOID

Schieb, H., Kratzin, H., Jahn, O., Mobius, W., Rabe, S., Staufenbiel, M., Wiltfang, J., Klafki, H. W.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.29 MB

english, 2011

48

Factors Responsible for Plasma β-Amyloid Accumulation in Chronic Kidney Disease

Gronewold, Janine, Klafki, Hans-Wolfgang, Baldelli, Enrico, Kaltwasser, Britta, Seidel, Ulla K., Todica, Olga, Volsek, Michaela, Haußmann, Ute, Wiltfang, Jens, Kribben, Andreas, Bruck, Heike, Hermann,

Journal:

Molecular Neurobiology

Year:

2016

Language:

english

File:

PDF, 272 KB

english, 2016

49

DIESTUFEN DES PÄDAGOGISCHEN DENKENS

Klafki, Wolfgang

Journal:

Bildung und Erziehung

Year:

1954

Language:

german

File:

PDF, 448 KB

german, 1954

50

The Amyloid-beta secondary structure distribution in CSF and blood measured by an immuno-IR-sensor: a novel biomarker candidate for Alzheimer’s disease

Nabers, Andreas, Ollesch, Julian, Schartner, Jonas, Kötting, Carsten, Genius, Just, Hafermann, Henning, Klafki, Hans-Wolfgang, Gerwert, Klaus, Wiltfang, Jens

Journal:

Analytical Chemistry

Year:

2016

Language:

english

File:

PDF, 1.35 MB

english, 2016